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ICAPS Cohorts

Clinical Trials – BP Response

Study Acronym Study Name Study Principal Investigator
ACEi-SS Pharmacogenomics of ACE inhibitors in Sardinia Nicola Glorioso
BB-SS Pharmacogenomics of Beta Blockers Sardinian Study Nicola Glorioso
GENRES GENes and Antihypertensive Drug RESponse Kimmo Kontula
GERA 1 Genetic Epidemiology of Responses to Antihypertensives 1 Stephen T. Turner
GERA 2 Genetic Epidemiology of Responses to Antihypertensives 2 Stephen T. Turner
HARP Hypertension and Ramipril Pharmacogenetics Study Jerome Rotter
IDEAL Identification of the Determinants of the Efficacy of Arterial Blood Pressure Lowering Drugs Francois Gueyffier
MIHYPHCTZ Milan Hypertension Pharmacogenomics of HCTZ Paolo Manunta
PEAR 1 Pharmacogenomic Evaluation of Antihypertensive Responses 1 Julie Johnson
PEAR 2 Pharmacogenomic Evaluation of Antihypertensive Responses 2 Julie Johnson
PHSS Pharmacogenomics of Hydrochlorothiazide Sardinian Study Nicola Glorioso
SOPHIA Pharmacogenomics of Losartan Nicola Glorioso

Clinical Trials – Adverse CV and Metabolic Outcomes

Study Acronym Study Name Study Principal Investigator
ACCORD Action to Control Cardiovascular Risk in Diabetes John B. Buse
ALLHAT / GENHAT The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial Donna Arnett
ASCOT Angloscandinavian Outcomes Trial Patricia Munroe / Mark Caulfield
CHIEF Chinese Hypertension Intervention Efficacy Study Wei Zhang
FEVER-PGx Pharmacogenomic Study of the Felodipine Event Reduction Wei Zhang
INVEST INternational VErapamil Trandolapril STudy Carl Pepine / Julie Johnson
NORDIL NORdic DILtiazem Study Anna F. Dominiczak
SPS3 Secondary Prevention of Small Subcortical Strokes Julie Johnson

Observational Studies – BP Response and/or Adverse Outcomes

Study Acronym Study Name Study Principal Investigator
CHARGE Cohorts for Heart and Aging Research in Genomic Epidemiology Bruce Psaty
CSN-StayOnDiur Campania Salute Network (CSN) – The StayOnDiur Study Bruno Trimarco
Estonia Biobank Estonian Genome Center, University of Tartu; population based biobank Andres Metspalu
GoDARTS Genetics of Diabetes and Audit Research Tayside Study Colin Palmer
GoShare Genetics of the Scottish Health Research Register Colin Palmer
GS-SFHS Generation Scotland-Scottish Family Health Study Colin Palmer / John Connell
LIFELINES LifeLines Cohort Study Harold Snieder
MESA Multi-Ethnic Study of Athersclerosis Jerome Rotter
SDS Khatri Sikh Diabetes Study (SDS) Dharambir K. Sanghera
Taichi Taiwan Metabochip Consortium Ida Chen
UCP Utrecht Cardiovascular Pharmacogenetics Anke-Hilse Maitland-Van der Zee